Concurrent Session-Banyan 1

Endothelial Cell Dysfunction in Kidney Disease

Friday, October 10, 2025

11:30 AM - 12:00 PM East Coast USA Time

Location: Banyan 1

Speaker(s)

Stephen J. Ruffenach, DO, MS, FACOI

Adjunct Clinical Assistant Professor of Preclinical Medicine
Burrell College of Osteopathic Medicine
Queen Creek, Arizona, United States

Moderator(s)

Mark D. Baldwin, DO, MACOI, FASN (he/him/his)

Professor and Chair Department of Primary Care Medicine
Arkansas Colleges of Health Education, College of Osteopathic Medicine
Fort Smith, Arkansas, United States

Disclosure(s):

Stephen J. Ruffenach, DO, MS, FACOI: No financial relationships to disclose

Mark D. Baldwin, DO, MACOI, FASN: No financial relationships to disclose

1.The Influence of Albuminuria on Mortality in Patients with Stable Coronary Artery Disease Scott D Solomon, Solomon,S, et al, Circulation Volume 116, Number suppl_16

2. Schmitz A, Vaeth M. Microalbuminuria: a major risk fac-
tor in non-insulin-dependent diabetes. A 10-year follow-up
study of 503 patients. Diabet Med 1988; 5: 126-134 [PMID:
2964977]

3. Mosenzon O, Wiviott SD, Heerspink HJL, et al. The Effect of Dapagliflozin on Albuminuria in DECLARE-TIMI 58. Diabetes Care. 2021;44(8):1805-1815. doi:10.2337/dc21-0076

Learning Objectives:

Understand the fundamental role of endothelial cells in vascular health.
Define endothelial cell dysfunction (ECD) and its key molecular mechanisms.
Appreciate the clinical implications of ECD for patient management