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Plenary

Advances & Challenges in the Management of Obesity, MASH, and Related Complications

Saturday, October 11, 2025
8:45 AM - 9:45 AM East Coast USA Time
Location: Calusa 1-6
Disclosure(s):
Andrew C. Buelt, DO: No financial relationships to disclose
Adams TD, Davidson LE, Litwin SE, Kim J, Kolotkin RL, Nanjee MN, Gutierrez JM, Frogley SJ, Ibele AR, Brinton EA, Hopkins PN, McKinlay R, Simper SC, Hunt SC. Weight and Metabolic Outcomes 12 Years after Gastric Bypass. N Engl J Med. 2017 Sep 21;377(12):1143-1155. doi: 10.1056/NEJMoa1700459. PMID: 28930514; PMCID: PMC5737957.

Peterli R, Wölnerhanssen BK, Vetter D, Nett P, Gass M, Borbély Y, Peters T, Schiesser M, Schultes B, Beglinger C, Drewe J, Bueter M. Laparoscopic Sleeve Gastrectomy Versus Roux-Y-Gastric Bypass for Morbid Obesity-3-Year Outcomes of the Prospective Randomized Swiss Multicenter Bypass Or Sleeve Study (SM-BOSS). Ann Surg. 2017 Mar;265(3):466-473. doi: 10.1097/SLA.0000000000001929. PMID: 28170356; PMCID: PMC5300030.

https://www.nejm.org/doi/full/10.1056/NEJMoa2032183

https://www.nejm.org/doi/full/10.1056/NEJMoa1411892

Learning Objectives:

  • Critically appraise current and emerging pharmacologic and interventional therapies for obesity
  • Critically appraise current and emerging pharmacologic and interventional therapies for metabolic dysfunction-associated steatohepatitis (MASH)
  • Identify ongoing challenges—including therapeutic access, adherence barriers, and disparities in care