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Concurrent Session-Calusa 1-6

Innovations in Rheumatology: The Cool, the Cutting-Edge, and the Clinically Relevant

Friday, October 10, 2025
4:00 PM - 4:30 PM East Coast USA Time
Location: Calusa 1-6
Disclosure(s):
Megan Eshbaugh, DO, FACOI: No financial relationships to disclose
Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, Bingham CO 3rd, Birnbaum NS, Burmester GR, Bykerk VP, Cohen MD, Combe B, Costenbader KH, Dougados M, Emery P, Ferraccioli G, Hazes JM, Hobbs K, Huizinga TW, Kavanaugh A, Kay J, Kvien TK, Laing T, Mease P, Ménard HA, Moreland LW, Naden RL, Pincus T, Smolen JS, Stanislawska-Biernat E, Symmons D, Tak PP, Upchurch KS, Vencovsky J, Wolfe F, Hawker G. 2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Ann Rheum Dis. 2010 Sep;69(9):1580-8. doi: 10.1136/ard.2010.138461. Erratum in: Ann Rheum Dis. 2010 Oct;69(10):1892. PMID: 20699241.

Peterson, D., Van Poppel, M., Boling, W. et al. Clinical safety and feasibility of a novel implantable neuroimmune modulation device for the treatment of rheumatoid arthritis: initial results from the randomized, double-blind, sham-controlled RESET-RA study. Bioelectron Med 10, 8 (2024). https://doi.org/10.1186/s42234-023-00138-x

Maz, M., Chung, S.A., Abril, A., Langford, C.A., Gorelik, M., Guyatt, G., Archer, A., Conn, D.L., Full, K.A., Grayson, P.C., Ibarra, M.F., Imundo, L.F., Kim, S., Merkel, P.A., Rhee, R.L., Seo, P., Stone, J.H., Sule, S., Sundel, R.P., Vitobaldi, O.I., Warner, A., Byram, K., Dua, A.B., Husainat, N., James, K.E., Kalot, M.A., Lin, Y.C., Springer, J.M., Turgunbaev, M., Villa-Forte, A., Turner, A.S. and Mustafa, R.A. (2021), 2021 American College of Rheumatology/Vasculitis Foundation Guideline for the Management of Giant Cell Arteritis and Takayasu Arteritis. Arthritis Rheumatol, 73: 1349-1365. https://doi.org/10.1002/art.41774

Fanouriakis A, Kostopoulou M, Andersen J, et al EULAR recommendations for the management of systemic lupus erythematosus: 2023 update Annals of the Rheumatic Diseases 2024;83:15-29.

Ohno, R., & Nakamura, A. (2024). Advancing Autoimmune Rheumatic Disease Treatment: CAR-T cell therapies - Evidence, safety, and future directions. Seminars in Arthritis and Rheumatism, 67, 152479. https://doi.org/10.1016/j.semarthrit.2024.152479
Zhang, Y., Han, W. Management of Cytokine Release Syndrome (CRS) following CAR T-cell therapy: a comprehensive review. Clin. Cancer Bull. 4, 15 (2025). https://doi.org/10.1007/s44272-025-00044-0

Learning Objectives:

  • Identifying some of the limitations of a rheumatoid factor in diagnosing rheumatoid arthritis and understanding some of the additional antibodies available
  • To become more familiar with molecular signature testing Understanding a novel new treatment for rheumatoid arthritis
  • Recognize newer biologic therapeutics used in rheumatology outside of rheumatoid arthritis