MarkAlain Déry, DO, MPH, FACOI: No financial relationships to disclose
Cohen MS, Chen YQ, McCauley M, et al. Antiretroviral Therapy for the Prevention of HIV-1 Transmission. N Engl J Med. 2016;375(9):830-839.
Grant RM, Lama JR, Anderson PL, et al. Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men. N Engl J Med. 2010;363(27):2587-2599.
Spinelli MA, Glidden DV, Mayer KH, et al. Doxycycline Prophylaxis for Bacterial Sexually Transmitted Infections. N Engl J Med. 2019;381(17):1595-1605.
Learning Objectives:
Explain the scientific basis and clinical implications of the U=U (Undetectable = Untransmittable) concept to improve patient counseling and reduce HIV-related stigma.
Evaluate the current guidelines and evidence supporting the use of PrEP and doxyPEP for HIV prevention, including patient selection, efficacy, and adherence strategies.
Identify barriers to equitable access and uptake of U=U, PrEP, and doxyPEP in diverse populations, and propose interventions to address disparities and optimize HIV prevention efforts.